The fixed dose combination (FDC) of imipenem (a potent, broad spectrum beta lactum antibiotic, resistant to degradation by bacterial ß-lactamases) and cilastatin (an inhibitor of dehydropeptidase I, an enzyme found in the brush border of the renal tubules), is given to prevent renal metabolism of imipenem and protect against its nephrotoxic effects. The combination is used in susceptible systemic bacterial infections and in surgical prophylaxis.
**All products sold will be shipped within india only. product will not be shipped to international destinations. Product will only be given on Current MRP Price.
Ingredients : Imipenem 500 mg + Cilastatin 500 mg
Packing : 1 Vial/Pack
Dosage : As directed by the physician.
Precautions: Renal impairment, CNS disorders, such as epilepsy, lactation & pregnancy.
Contraindications: Hypersensitivity to beta-lactam antibiotics, local anaesthetics of the amide type and in patients with severe shock or heart block.
Side Effects: Nausea, vomiting, diarrhoea, antibiotic associated colitis, taste disturbances, tooth or tongue discolouration, hearing loss, blood disorders, (decreased haematocrit,increased prothrombin time), allergic reactions including rash, pruritus, urticaria, erythema, Steven’s-Johnson syndrome, fever, anaphylactic reactions, toxic epidermal necrolysis, exfoliative dermatis, myoclonic activity, convulsions, confusion and mental disturbances, slight increase in liver enzymes and bilirubin, rarely, hepatis, increase in serum creatinine and blood urea, red coloration of urine in children.
Storage Conditions: Store it at room temperature and in an airtight container. Keep away from light and children.